Palo Alto Cortex XDR vs Trellix Endpoint Security
Side-by-side from the Top 11 ranking of CrowdStrike Falcon vs Microsoft Defender for Endpoint: 11 Best Endpoint Protection Software 2026. Last verified July 4, 2026.
The short answer
Palo Alto Cortex XDR ranks higher on Top 11 (#4 vs #9) for IT and security leaders. Fuses endpoint, network, and cloud into one XDR.
At a glance
| Palo Alto Cortex XDR | Trellix Endpoint Security | |
|---|---|---|
| Top 11 rank | #4 / CrowdStrike Falcon vs Microsoft Defender for Endpoint: 11 Best Endpoint Protection Software 2026 | #9 / CrowdStrike Falcon vs Microsoft Defender for Endpoint: 11 Best Endpoint Protection Software 2026 |
| Score (out of 9.4) | 8.9 | 8.2 |
| Best for | Best for network plus endpoint XDR | Best for large existing McAfee estates |
| Pricing | $$$ (custom, per-endpoint enterprise pricing) | $$ (custom, per-endpoint enterprise pricing) |
| HQ | Santa Clara, USA | San Jose, USA |
| Founded | 2005 | 2022 |
Palo Alto Cortex XDR
Fuses endpoint, network, and cloud into one XDR.
www.paloaltonetworks.com/cortex/cortex-xdrTrellix Endpoint Security
Mature McAfee and FireEye platform for large estates.
www.trellix.com/products/endpoint-security/Methodology and scoring weights live at /methodology. No vendor pays for placement — see about.